General Cell Based Assays
Meso Scale Discovery RPLEX HUM Folate R alpha ASY
The Meso Scale Discovery R-Plex Human Folate R-alpha Assay Kit is a multiplex immunoassay for measuring folate receptor alpha in human serum plasma and cell culture supernatant It uses electrochemiluminescent detection for high sensitivity broad dynamic range and precision with low sample use The kit includes a 96-well plate with capture antibody detection antibody read buffer calibrator and controls for quantifying folate receptor alpha a key biomarker in human samples
Eurofins Discoverx AssayComplete Thawing Reagent T10, 100. (92-4110TR)
AssayComplete Thawing Reagent T10 is an optimized thawing reagent for revival and recovery of Eurofins DiscoverX cell lines. This reagent ensures optimal post-thaw viability, recovery and assay performance upon thawing. This product is provided as a bottle of 100 mL. Please refer to cell line specific datasheet to determine the recommended thawing reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Raybiotech Inc Human Sp1 Activity Assay Kit, 1 Plate Kit
RayBio® Human Sp1 Transcription Factor Activity Assay. This assay uses a dsDNA coated plate with canonical Sp1 binding sequences to semi-quantitatively detect active Sp1 in lysates or nuclear extracts. Dry ice shipment (additional fee).
Eurofins Discoverx PathHunter eXpress OPRK1 Total Internalization Assay, 2pl Kit. (93-0828E3CP0M)
The PathHunter OPRK1 Total Internalization eXpress kit provides an easy to-use cell based assay to study drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This kit uses EFC technology to measure ligand-induced internalization of OPRK1 via detection of localization to the early endosome. The included cell line overexpresses EA-tagged OPRK1 and a ProLink-tagged early endosome protein. Upon ligand-induced receptor activation, resulting internalization of the OPRK1 receptor to the early endosome leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mCCR6 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0694E2MCP2M)
The PathHunter mCCR6 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL20/MIP-3α) based activation of mCCR6 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCCR6 and EA-tagged β-Arrestin-2. Activation of mCCR6 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Calcium Assay kit (Fluorometric)
Calcium Assay kit (Fluorometric)
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress mAGTRL1 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0565E2MCP0M)
The PathHunter mAGTRL1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. apelin-13) based activation of mAGTRL1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mAGTRL1 and EA-tagged β-Arrestin-2. Activation of mAGTRL1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Electron Microscopy Sciences Flim Sleeve 135 mm/24 exp with Frosted Open Flap
Polyguard Polypropylene film sleeves are the finest archival quality material, and are guaranteed to give you ultimate protection for your most important film negatives. Polyguard is 100% acid free, as well as being free from optical distortion. It is resistant to water, grease, oil, alkalies, and organic solvents. Polyguard is durable, yet pliable and gentle to the film and will not become brittle, crack, or abrade the film.
Type: Frosted Open Flap
Eurofins Discoverx cAMP Hunter eXpress TACR3 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0092E2CP2M)
The cAMP Hunter TACR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. senktide, neurokinins) based activation of TACR3 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type TACR3, a naturally Gs coupled GPCR. Upon activation of TACR3, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Sigma Aldrich Fine Chemicals Biosciences fluorometric Intracellular
Reactive oxygen species (ROS) are generated as a result of the reduction of oxygen during aerobic respiration and by various enzymatic systems within the cell. At physiological levels ROS contribute to cell signaling and host defense. Increased ROS generation above the detoxification capacity of the biological system results in oxidative stress and cellular damage. The main damage to cells results from the ROS-induced alteration of macromolecules such as polyunsaturated fatty acids in membrane lipids essential proteins and DNA. ROS has been implicated in disease states such as Alzheimer disease Parkinson disease cancer and aging.
Eurofins Discoverx PathHunter eXpress MTNR1B CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0630E2CP0M)
The PathHunter MTNR1B eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. melatonin) based activation of MTNR1B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MTNR1B and EA-tagged β-Arrestin-2. Activation of MTNR1B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress rDRD1 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0620E2CP2L)
The PathHunter rDRD eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine) based activation of rDRD GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged rDRD and EA-tagged β-Arrestin-2. Activation of rDRD stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Rat version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR3 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0626E2CP1M)
The PathHunter GPR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR3 and EA-tagged β-Arrestin-2. Activation of GPR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx AssayComplete Cell Plating 7 Reagent, 500. (93-0563R7B)
AssayComplete Cell Plating 7 Reagent is an optimized cell plating reagent for use in plating of Eurofins DiscoverX cell lines for assays. This reagent was optimized for maximal cell health and ligand responsiveness during assays while eliminating hormones and growth components which may lead to increased basal activity. This product is provided as a bottle of 500 mL. Please refer to cell line specific datasheet to determine the recommended cell plating reagent. For detailed product information, User manual and datasheet, visit www.discoverx.com/reagents.
Eurofins Discoverx PathHunter PL/PK Detection kit, 4,000 dp (384-well). (93-0812)
The PathHunter ProLabel/PK Detection kit is a detection kit intended for use with Eurofins DiscoverX's PathHunter cell lines or with custom cell lines overexpressing ED (ProLabel/PK) but not containing any EA. This kit contains lysis buffer, exogenous EA, and EFC substrate to allow for detection of levels of ED in the assayed cells. This kit contains all components required to assay 10 plates (96/384-well). For detailed product information, User manual and COA, visit www.discoverx.com/products/reagents/detection-kit-93-0812.